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Giving Contact English Japanese HOME About LiMe Faculty Research Joint Usage/Research Center Graduate Program Job Opportunities About Message from the Director Prize History Organization Publications Research Achievements Shared Research Facilities at LiMe LATEST RESEARCH RESULTS Jan 31, 2023Murine breast cancers disorganize the liver transcriptome in a zonated manner Nov 09, 2022Successful establishment and development of efficient clinical human ES cell lines and banking of cell lines Nov 02, 2022Development of an in vivo cleavable donor plasmid for targeted transgene integration by CRISPR-Cas9 and CRISPR-Cas12a Jun 22, 2022Revealing primate-unique extraembryonic differentiation route by stem cell modeling Feb 08, 2022Identify the origin of diverse cellular responses in signal transduction pathway by integrating theoretical and experimental methods Jun 16, 2021Establishment of a clinical-grade human embryonic stem cell line KthES11 May 10, 2021A new mechanism of regulatory T cell generation to suppress excessive immune responses ―Non-coding DNA sequences indispensable for immune tolerance were discoveredー Feb 25, 2021Complete control of a gene regulatory network of ascidian embryo by a few factors identified by a mathematical theory. Nov 26, 2020The development of an antiviral drug screening platform with a FRET biosensor for measurement of arenavirus Z assembly Oct 22, 2020Endogenous retroviruses drive KRAB zinc-finger protein family expression for tumor suppression Sep 14, 2020Molecular mechanism of cross-species transmission of primate lentiviruses ―Principle of lentiviral cross-species transmission leading to the emergence of the AIDS virus― Sep 07, 2020Identification of a viral factor that impairs immune responses in COVID-19 patients Sep 07, 2020A clustering-independent method for finding differentially expressed genes in single-cell transcriptome data Jul 15, 2020Multiomics investigation revealing the characteristics of HIV-1-infected cells in vivo ―Clues for the development of an “HIV-1 cure”－ Jul 10, 2020Requirement of TCR signal for γδ T cell homeostasis in peripheral organs Jul 07, 2020Competition between STAT5 and phosphatidylinositol 3-kinase under IL-7 receptor signaling modulates T cell development and homeostasis Mar 09, 2020Development of a novel in silico experimental platform for bone remodeling Oct 17, 2019A mechanism inhibiting a cartilage formation in the heart Aug 27, 2019Self-organized formation of limb bud from pluripotent stem cells Jun 26, 2019Identification of a genomic enhancer that enforces proper apoptosis induction in thymic negative selection Joint Usage / Research Center “Joint Usage/ Research Center Program for Transdisciplinary Collaboration on Viral Research, Stem Cell Science and System Biology” has been designated by the Ministry of Education, Culture, Sports, Science and Technology within our institute. We offer our resources and research techniques to research communities in Japan and overseas through joint research initiatives. RESEARCH TEAMS Department of Virus Research Department of Regeneration Science and Engineering Department of Biosystems Science Research Center for Infectious Diseases Center for Animal Experiments Center for Human ES Cell Research INFORMATIONMore May 02, 2023 公募情報 Call for Applications: Specially Appointed Researcher (Full Time) Nov 08, 2022 NEWS Call for proposals: Joint Usage/ Research Center Programs (FY2023) Apr 04, 2022 NEWS The institute name has changed Jan 18, 2022 NEWS Annual Report ( Volume 5 2020 ) available now Nov 12, 2021 NEWS Call for proposals: Joint Usage/ Research Center Programs (FY2022) SEMINAR / EVENTMore Dec 14, 2021Seminar 【Theoretical Biology Seminar】Mathematical Modeling of Drug Resistance Evolution and The Optimal Treatment Strategy in EGFR mutated Lung Cancer Feb 5, 2020Seminar No.1313 HTLV-1 Molecular Pathogenesis: From Hbz to CTCF Feb 3, 2020Seminar “An in vitro model to evaluate skeletal muscle cell function: myokine secretion and satellite cell myogenesis” Jan 27, 2020Seminar No.1312　How does HTLV-1 hide? Dynamics of HTLV-1 transcriptional latency and reactivation Jan 7, 2020Seminar Modelling membrane-bound cellular organelles with non-equilibrium dynamics 53 Shogoin Kawahara-cho, Sakyo-ku, Kyoto 606-8507 JAPAN TEL: +81-75-751-3802 © Institute for Life and Medical Sciences, Kyoto University. All Rights Reserved. Staff only | Site Policy / Privacy Policy HOME About LiMe Message Prize History Organization Publications Faculty Research Achievements Shared Research Facilities at LiMe Joint Usage/Research Center Graduate Program Job Opportunities Contact Giving Close